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|Stan Wawrinka of Switzerland poses with the trophy during the ceremony after winning the men's singles final match against Novak Djokovic of Serbia at the French Open tennis tournament at the Roland Garros stadium in Paris Nick Martin Limited Jersey , France on June 7, 2015.[PhotoAgencies] PARIS - There were no jeers this time as Swiss Stan Wawrinka defied the odds to win the French Open with a courageous 4-6 6-4 6-3 6-4 victory over world number one Novak Djokovic in an enthralling final on Sunday.
The eighth seed, booed by the crowd when he played French opponents this year, handed Serbian Djokovic his third defeat in three Roland Garros finals to add a second major to his 2014 Australian Open title.
"I played the match of my life, it's hard to believe. Playing against Novak was one of the biggest challenges. I know how much he wanted this Roland Garros Will Fuller V Limited Jersey ," Wawrinka said courtside.
"It was a crazy atmosphere these two weeks. I'd like to thank you."
Wawrinka used his superb one-handed backhand to devastating effect, hitting flat groundstrokes that wore down eight-times grand slam champion Djokovic, who was looking to complete a career grand slam in Paris.
He sealed victory on his second match point with his 60th winner, a flashing backhand down the line that made him the second Swiss player to prevail Porte d'Auteuil after Roger Federer in 2009.
Unbeaten on clay this season, Djokovic threatened Wawrinka on his serve early on and he converted his third break chance when the Swiss served a double fault.
The Australian Open champion wasted two set points by playing too casually Julien Davenport Limited Jersey , and had a break point against him, which he saved with a service winner. He had a third set point that he converted when Wawrinka's forehand sailed long.
By Atsushi Ebihara
KOBE, Japan Oct. 31 (Xinhua)-- Prior to the world's first transplantation of human induced pluripotent stem (iPS) cells to regenerate human retinas, the leader of a research team at an institute in this western Japanese city has argued that shortening the production period for autologous iPS cells and reducing costs will be key to spurring developments in regenerative medicine, in the hope that more research using iPS-derived cells will be carried out for other diseases in the near future.
The new clinical research will be conducted by a group led by Dr. Masayo Takahashi at the Laboratory for Retinal Regeneration D'Onta Foreman Limited Jersey , RIKEN Center for Developmental Biology. Her team now plans to transplant autologous iPS-cell derived retinal pigment epithelium (RPE) cell sheets into patients with exudativeage-related macular degeneration to check the safety and feasibility of the technique, which is expected to become a new therapy to improve vision.
According to the institute, the eye disease is the most common cause of visualimpairment in the elderly and affects up to 1 percent of people over 50 years of age in Japan.
Commencing the clinical research this autumn, the ophthalmologist expressed in a recent interview with Xinhua her confidence that the pilot scheme will succeed. She stressed that her team's technology ensures the safety of the newly-created iPS cell-derived RPE cells for the new treatment.
To ensure safety, Takahashi said her team has recently begun selecting suitable test subjects to produce autologous iPS cells before transplanting them into human bodies a year later. The primary goal of their research is to find out whether the cells have the potential to form tumors or not. She added that the safe use of iPS cell-derived RPE cells has been repeatedly observed in similar tests using animals such as rats and mice. "Many researchers in the world have become concerned that iPS cell-derived cells have the potential to multiply themselves and create tumors Zach Cunningham Limited Jersey , so our study must demonstrate that the donor cells are medically safe and will survive in the bodies over the following period,"she added, "We will see the results by 2017, observing a total of six patients."
Takahashialso noted that her team will use"purified" iPS cell- derived cells where no original iPS cells are observed. She attributed the purification process' successful completion to the special character of RPE cells. "Because epithelial cells are usually brown, it is relatively easier for us to purify the iPS cell-derived RPE cells than many other iPS cell-derived cells from the human body Deshaun Watson Limited Jersey ,"she said."Our team could produce the safe cells thanks to the color."
As a secondary goal, Takahashi emphasized that her team will see whether the new products are effective or commercially viable as therapy for patients with wet-typeage-related macular degeneration, of whom there are around 600,000 in Japan.
She said the production and validation of the autologous iPS cells and subsequent RPE cell sheets will take approximately 10 months, stating that this period of time is too long to cope with all such patients at once. "If we need 10 months Women's Tyler Ervin Jersey , we can cover only one or two patients per year, meaning that the method simply isn't suitable as a practical therapy, and our next challenge is to shorten the production time,"she said.
Regarding the production period, Takahashi also noted that her team will step up their efforts to develop techniques for producing a so-called"iPS stock Women's Braxton Miller Jersey ,"aiming to introduce an allogeneic transplantation method instead of the current auto- transplantation method. She expects the new production process will take only three to four months before actual transplantation. "If we are able to prepare several types of iPS cell-derived RPE cells according to leukocyte type in advance, we can expect to speed up the transplantation process using allogeneic transplantation,"she added."In addition, the allogeneic transplantation method we anticipate will also save a lot on treatment costs, perhaps millions of yen."
Regarding other diseases which iPS cell-derived cells may be effective at treating Women's Keke Coutee Jersey , Takah. Wholesale Jerseys China Cheap Jerseys China Free Shipping Cheap Hats Cheap Jerseys Online Cheap NCAA Jerseys Cheap T-shirts Cheap NHL T-shirts Cheap NFL Hoddies Cheap Baseball Shirts Cheap T-shirts China